“active site”的概念、定义、翻译、参考文献-科学参考

active site

Chemistry

1. A site on the surface of a catalyst at which activity occurs.
2. The site on the surface of an enzyme molecule that binds the substrate molecule. The properties of an active site are determined by the three-dimensional arrangement of the polypeptide chains of the enzyme and their constituent amino acids. These govern the nature of the interaction that takes place and hence the degree of substrate specificity and susceptibility to inhibition.

Chemical Engineering

1. An available location on the surface of a catalyst available for reactants to bind and result in a chemical reaction taking place. The active site can be blocked by a chemical agent or poison thereby reducing the effectiveness of the catalyst.

2. On the surface of an enzyme, the active site is the location to which a substrate binds. The binding of the substrate to the enzyme is dependent on the conformation or 3-D shape of the protein. Inhibition prevents the binding from taking place by altering the conformation thereby preventing the substrate from binding, or by blocking the site.

Biology

The site on the surface of an enzyme molecule that binds and acts on the substrate molecule. The properties of an active site are determined by the three-dimensional arrangement of the polypeptide chains of the enzyme and their constituent amino acids. These govern the nature of the interaction that takes place and hence the degree of substrate specificity and susceptibility to inhibition. Binding of the substrate involves the formation of weak bonds between it and the enzyme, which induces subtle changes in shape of the active site so it fits more tightly around the substrate—a so-called induced fit mechanism.

单词	active site
释义	active site Chemistry 1. A site on the surface of a catalyst at which activity occurs. 2. The site on the surface of an enzyme molecule that binds the substrate molecule. The properties of an active site are determined by the three-dimensional arrangement of the polypeptide chains of the enzyme and their constituent amino acids. These govern the nature of the interaction that takes place and hence the degree of substrate specificity and susceptibility to inhibition. Chemical Engineering 1. An available location on the surface of a catalyst available for reactants to bind and result in a chemical reaction taking place. The active site can be blocked by a chemical agent or poison thereby reducing the effectiveness of the catalyst. 2. On the surface of an enzyme, the active site is the location to which a substrate binds. The binding of the substrate to the enzyme is dependent on the conformation or 3-D shape of the protein. Inhibition prevents the binding from taking place by altering the conformation thereby preventing the substrate from binding, or by blocking the site. Biology The site on the surface of an enzyme molecule that binds and acts on the substrate molecule. The properties of an active site are determined by the three-dimensional arrangement of the polypeptide chains of the enzyme and their constituent amino acids. These govern the nature of the interaction that takes place and hence the degree of substrate specificity and susceptibility to inhibition. Binding of the substrate involves the formation of weak bonds between it and the enzyme, which induces subtle changes in shape of the active site so it fits more tightly around the substrate—a so-called induced fit mechanism.
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