“pan FGFR inhibitor ARQ 087”的概念、定义、翻译、参考文献-科学参考

An orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor ARQ 087 binds to and potently inhibits the activity of FGFR subtypes 1, 2 and 3. This may result in the inhibition of FGFR-mediated signal transduction pathways, tumor cell proliferation, tumor angiogenesis and tumor cell death in FGFR-overexpressing tumor cells. FGFR, a receptor tyrosine kinase, is upregulated in many tumor cell types and plays a key role in tumor cellular proliferation, differentiation, angiogenesis and survival.

单词	pan FGFR inhibitor ARQ 087
释义	pan FGFR inhibitor ARQ 087 An orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor ARQ 087 binds to and potently inhibits the activity of FGFR subtypes 1, 2 and 3. This may result in the inhibition of FGFR-mediated signal transduction pathways, tumor cell proliferation, tumor angiogenesis and tumor cell death in FGFR-overexpressing tumor cells. FGFR, a receptor tyrosine kinase, is upregulated in many tumor cell types and plays a key role in tumor cellular proliferation, differentiation, angiogenesis and survival.
随便看	Linzess Lioresal liothyronine sodium lipegfilgrastim lipid lipid Lipiodol Lipitor LipoDox Lipo-Lutin lipoma lipophilic lipoprotein liposarcoma liposomal liposomal amphotericin B liposomal annamycin liposomal belotecan liposomal cisplatin liposomal c-raf antisense oligonucleotide liposomal curcumin liposomal cytarabine liposomal cytarabine-daunorubicin CPX-351 liposomal daunorubicin citrate liposomal docetaxel