“zirconium Zr 89 Df-IAB2M”的概念、定义、翻译、参考文献-科学参考

A radioimmunoconjugate comprised of an antibody fragment (IAB2M) against prostate-specific membrane antigen (PSMA), conjugated to the chelator desferrioxamine (Df) and labeled with the radioisotope zirconium Zr 89, with potential positron emission tomography (PET) imaging activity. Upon administration of zirconium Zr 89 Df-IAB2M, the antibody moiety binds to the extracellular domain of PSMA expressed on cancer cells. This may enable PET detection of the radioisotope moiety, and allows the imaging and quantification of PSMA-expressing tumor cells. PSMA is a cell surface peptidase highly expressed by malignant prostate epithelial cells and vascular endothelial cells in various solid tumor malignancies.

单词	zirconium Zr 89 Df-IAB2M
释义	zirconium Zr 89 Df-IAB2M A radioimmunoconjugate comprised of an antibody fragment (IAB2M) against prostate-specific membrane antigen (PSMA), conjugated to the chelator desferrioxamine (Df) and labeled with the radioisotope zirconium Zr 89, with potential positron emission tomography (PET) imaging activity. Upon administration of zirconium Zr 89 Df-IAB2M, the antibody moiety binds to the extracellular domain of PSMA expressed on cancer cells. This may enable PET detection of the radioisotope moiety, and allows the imaging and quantification of PSMA-expressing tumor cells. PSMA is a cell surface peptidase highly expressed by malignant prostate epithelial cells and vascular endothelial cells in various solid tumor malignancies.
随便看	Weightlessness Weightlessness Welchol Wellbutrin Wellcovorin well-differentiated well-differentiated lymphocytic lymphoma Wermer syndrome Western medicine wheatgrass juice whey protein isolate whey protein powder Whipple procedure white blood cell white button mushroom extract white carrot White Hole white wine Whitmore-Jewett staging system WHO whole-brain radiation therapy whole-brain radiotherapy whole cell vaccine whole-exome sequencing whole-genome sequencing