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单词 prodrug
释义
prodrug

Chemistry
  • A compound that becomes an active drug after metabolism has taken place. Prodrugs are used extensively in medicine became they can improve the drug’s ability to interact selectively with the cells that are targeted, thus reducing undesirable side effects.


Biology
  • A drug that requires further metabolism in the liver before becoming biologically active. An example of a prodrug is the immunosuppressant azathioprine, which is metabolized in the body to the active compound 6-mercaptopurine.


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