“MET tyrosine kinase inhibitor PF-04217903”的概念、定义、翻译、参考文献-科学参考

An orally bioavailabe, small-molecule tyrosine kinase inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor PF-04217903 selectively binds to and inhibits c-Met, disrupting the c-Met signaling pathway, which may result in the inhibition of tumor cell growth, migration and invasion of tumor cells, and the induction of death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays key roles in tumor cell proliferation, survival, invasion, metastasis, and tumor angiogenesis. Check foractive clinical trials using this agent.

单词	MET tyrosine kinase inhibitor PF-04217903
释义	MET tyrosine kinase inhibitor PF-04217903 An orally bioavailabe, small-molecule tyrosine kinase inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor PF-04217903 selectively binds to and inhibits c-Met, disrupting the c-Met signaling pathway, which may result in the inhibition of tumor cell growth, migration and invasion of tumor cells, and the induction of death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays key roles in tumor cell proliferation, survival, invasion, metastasis, and tumor angiogenesis. Check foractive clinical trials using this agent.
随便看	Benemid Beneo Synergy 1 benign benign breast disease benign proliferative breast disease benign prostatic hyperplasia benign tumor benign vascular tumor Benlysta Benoquin benthic zone benzaldehyde benzaldehyde dimethane sulfonate benzene benzo(a)pyrene benzodiazepine benzoylphenylurea benzydamine benzydamine hydrochloride BEP BEP regimen berberine chloride bereavement bergamot Bernoulli's theorem