“cyclosporine ophthalmic emulsion”的概念、定义、翻译、参考文献-科学参考

An topical ophthalmic formulation containing cyclosporine, an undecapeptide produced by the fungus Beauveria nivea, with immunosuppressant and anti-inflammatory activities. The exact therapeutic mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release.

单词	cyclosporine ophthalmic emulsion
释义	cyclosporine ophthalmic emulsion An topical ophthalmic formulation containing cyclosporine, an undecapeptide produced by the fungus Beauveria nivea, with immunosuppressant and anti-inflammatory activities. The exact therapeutic mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release.
随便看	Inderal indeterminate indeterminate cleavage indeterminate growth index case Index of refraction Indian cress Indian elm Indian rhubarb Indian saffron Indian valerian indibulin indication indicine-N-oxide indinavir indinavir sulfate indirect ophthalmoscopy Indium 111 ProstaScint indium In 111 anti-CD45 monoclonal antibody BC8 indium In 111 anti-CEA monoclonal antibody M5A indium In 111 anti-EGFR monoclonal antibody ABT-806 indium In 111 bevacizumab indium In 111 capromab pendetide indium In 111 chimeric monoclonal antibody 806 indium In 111 CHX-A DTPA trastuzumab