“TLR4 agonist GLA-SE”的概念、定义、翻译、参考文献-科学参考

A synthetic lipid A derivative and toll-like receptor 4 (TLR4) agonist, in an oil-in-water emulsion, with potential immunoadjuvant activity. Upon administration, GLA-SE binds to and activates TLR4, thereby stimulating dendritic cells (DCs), monocytes and macrophages. This activation results in the production of proinflammatory cytokines, including interferon alpha, tumor necrosis factor-alpha and the interleukins (IL), IL-1 beta, -6 and -12. This may induce a T helper cell-1 (Th1) immune response and activates a cytotoxic T-lymphocyte (CTL) response against tumor associated antigens (TAAs) upon co-administration of vaccine antigens. TLR4, a member of the TLR family, plays a key role in the activation of innate immunity.

单词	TLR4 agonist GLA-SE
释义	TLR4 agonist GLA-SE A synthetic lipid A derivative and toll-like receptor 4 (TLR4) agonist, in an oil-in-water emulsion, with potential immunoadjuvant activity. Upon administration, GLA-SE binds to and activates TLR4, thereby stimulating dendritic cells (DCs), monocytes and macrophages. This activation results in the production of proinflammatory cytokines, including interferon alpha, tumor necrosis factor-alpha and the interleukins (IL), IL-1 beta, -6 and -12. This may induce a T helper cell-1 (Th1) immune response and activates a cytotoxic T-lymphocyte (CTL) response against tumor associated antigens (TAAs) upon co-administration of vaccine antigens. TLR4, a member of the TLR family, plays a key role in the activation of innate immunity.
随便看	hematopoietic stem cell hematopoietic tissue hematoporphyrin derivative hematuria heme heme hemiasterlin analogue E7974 hemihypertrophy hemilaryngectomy hemizygous hemochromatosis hemoglobin hemolymph hemolysis hemophagocytic lymphohistiocytosis hemophilia hemophilia hemoptysis hemorrhage hemorrhagic cystitis hemorrhoid henatinib maleate heparan sulfate glycosaminoglycan mimetic M402 heparan sulfate glycosaminoglycan mimetic nanopolymer mouthwash heparin