An abbreviation for a chemotherapy combination used to treat colorectal cancer that has spread to other parts of the body. It is also used to treat esophageal cancer and stomach cancer that are advanced or have spread to other parts of the body. It includes the drugs capecitabine (Xeloda) and irinotecan hydrochloride. Also called CAPIRI, XELIRI, and XELIRI regimen. OR A regimen consisting of capecitabine and oxaliplatin used as a treatment for advanced stage colorectal cancer. This regimen differs from a similar regimen, XELOX, with regards to the dosing schedule for oxaliplatin.