“nucleoside analog DFP-10917”的概念、定义、翻译、参考文献-科学参考

单词	nucleoside analog DFP-10917
释义	nucleoside analog DFP-10917 A deoxycytosine analog with potential antineoplastic activity. Upon administration, DFP-10917 is phosphorylated to generate its nucleotide form, which functions as a deoxycytosine mimic and is incorporated into DNA in tumor cells. This causes DNA strand breaks during polymerization due to beta-elimination during the fidelity checkpoint, which results in G2/M phase-arrest and tumor cell apoptosis.
随便看	GVHD GW572016 GW786034 GWAS gymnosperm gynecologic gynecologic cancer gynecologic oncologist gynecologist gynecomastia Gyne-Lotrimin H1299 tumor cell lysate vaccine hA20 HAART habitat habituation Haelan 951 Haemophilus influenzae b vaccine hafnium oxide-containing nanoparticles NBTXR3 hair follicle hairy cell leukemia Halaven Haldol Half-life Half-Life

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