“bi-functional alkylating agent VAL-083”的概念、定义、翻译、参考文献-科学参考

单词	bi-functional alkylating agent VAL-083
释义	bi-functional alkylating agent VAL-083 A bi-functional alkylating agent, with potential antineoplastic activity. Upon administration, VAL-083 crosses the blood brain barrier (BBB) and appears to be selective for tumor cells. This agent alkylates and crosslinks DNA which ultimately leads to a reduction in cancer cell proliferation. In addition, VAL-083 does not show cross-resistance to other conventional chemotherapeutic agents and has a long half-life in the brain. Check for active clinical trialsusing this agent.
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