“tucotuzumab celmoleukin”的概念、定义、翻译、参考文献-科学参考

A recombinant fusion protein comprised of a human monoclonal antibody directed against the epithelial cell adhesion molecule (EpCAM or KS) linked to an active interleukin-2 (IL2) molecule with potential antineoplastic activity. The humanized monoclonal antibody moiety of tucotuzumab celmoleukin recognizes and binds to EpCAM, a cell surface epithelial protein that is expressed on a wide variety of cancer cells, thereby concentrating IL2 in EpCAM-expressing tumor tissue. Subsequently, the localized IL2 moiety of this fusion protein may stimulate a cytotoxic T-cell antitumor immune response.

单词	tucotuzumab celmoleukin
释义	tucotuzumab celmoleukin A recombinant fusion protein comprised of a human monoclonal antibody directed against the epithelial cell adhesion molecule (EpCAM or KS) linked to an active interleukin-2 (IL2) molecule with potential antineoplastic activity. The humanized monoclonal antibody moiety of tucotuzumab celmoleukin recognizes and binds to EpCAM, a cell surface epithelial protein that is expressed on a wide variety of cancer cells, thereby concentrating IL2 in EpCAM-expressing tumor tissue. Subsequently, the localized IL2 moiety of this fusion protein may stimulate a cytotoxic T-cell antitumor immune response.
随便看	palpation palpitation Pamelor pamidronate disodium Pamolyn 300 panacea pan-AKT inhibitor ARQ 751 pan-AKT kinase inhibitor GSK690693 Pancoast tumor pancreas pancreas Pancrease pancreatectomy pancreatic pancreatic cancer pancreatic duct pancreatic endocrine cancer pancreatic endocrine tumor pancreatic enzyme pancreatic function test pancreatic insulin-producing tumor pancreatic juice pancreatic neuroendocrine tumor pancreatic polypeptide pancreatic tumor