“TLR9 agonist MGN1703”的概念、定义、翻译、参考文献-科学参考

A synthetic oligonucleotide based on a proprietary double stem-loop immunomodulator design with potential immunostimulating activity. TLR9 agonist MGN1703 binds to and activates intracellular Toll-like receptor 9 (TLR9) in monocytes/macrophages, plasmacytoidal and myeloid dendritic cells (DCs), and natural killer (NK) cells, initiating immune signaling pathways and inducing T-helper 1 cell (Th1) production leading to the production of memory T cells and a Th1-mediated immune response. By activating the immune system, MGN1703 may attack tumor associated antigen (TAAs). TLR9 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity.

单词	TLR9 agonist MGN1703
释义	TLR9 agonist MGN1703 A synthetic oligonucleotide based on a proprietary double stem-loop immunomodulator design with potential immunostimulating activity. TLR9 agonist MGN1703 binds to and activates intracellular Toll-like receptor 9 (TLR9) in monocytes/macrophages, plasmacytoidal and myeloid dendritic cells (DCs), and natural killer (NK) cells, initiating immune signaling pathways and inducing T-helper 1 cell (Th1) production leading to the production of memory T cells and a Th1-mediated immune response. By activating the immune system, MGN1703 may attack tumor associated antigen (TAAs). TLR9 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity.
随便看	optic tract optimism OptiPrep Optison Oracit oral oral aminolevulinic acid hydrochloride oral and maxillofacial surgeon oral azacitidine oral cancer oral cavity oral cavity cancer oral chemotherapy oral contraceptive pill Oralet oral fludarabine phosphate oral Hsp90 inhibitor IPI-493 oral microencapsulated diindolylmethane oral milataxel oral picoplatin oral rehydration solution oral sodium phenylbutyrate oral surgeon oral topotecan hydrochloride Oramorph