“lamivudine”的概念、定义、翻译、参考文献-科学参考

A synthetic nucleoside analogue with activity against hepatitis B virus (HBV) and HIV. Intracellularly, lamivudine is phosphorylated to its active metabolites, lamiduvine triphosphate (L-TP) and lamiduvine monophosphate (L-MP). In HIV, L-TP inhibits HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleoside analogue into viral DNA. In HBV, incorporation of L-MP into viral DNA by HBV polymerase results in DNA chain termination. L-TP is a weak inhibitor of mammalian DNA polymerases alpha and beta, and mitochondrial DNA polymerase. or A drug used to treat infection caused by viruses.

单词	lamivudine
释义	lamivudine A synthetic nucleoside analogue with activity against hepatitis B virus (HBV) and HIV. Intracellularly, lamivudine is phosphorylated to its active metabolites, lamiduvine triphosphate (L-TP) and lamiduvine monophosphate (L-MP). In HIV, L-TP inhibits HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleoside analogue into viral DNA. In HBV, incorporation of L-MP into viral DNA by HBV polymerase results in DNA chain termination. L-TP is a weak inhibitor of mammalian DNA polymerases alpha and beta, and mitochondrial DNA polymerase. or A drug used to treat infection caused by viruses.
随便看	attenuated Listeria monocytogenes CRS-100 ATT/RHT attributable risk atypia atypical ductal breast hyperplasia atypical ductal hyperplasia atypical glandular cells atypical glandular cells of uncertain significance atypical glandular cells of undetermined significance atypical hyperplasia atypical lobular breast hyperplasia atypical lobular hyperplasia atypical mole atypical squamous cells, cannot exclude a high-grade lesion atypical squamous cells of undetermined significance atypical teratoid/rhabdoid tumor auditory auditory brain stem response test Augmentin augmerosen auranofin auricular Aurimmune Aurolate Aurora A kinase inhibitor TAS-119