“anti-MUC1 CAR-transduced autologous T lymphocytes”的概念、定义、翻译、参考文献-科学参考

Autologous T lymphocytes transduced with a retroviral vector expressing a chimeric antigen receptor (CAR) consisting of a single chain variable fragment (scFv) against the human tumor-associated epithelial antigen mucin 1 (MUC1), with potential immunomodulating and antineoplastic activities. Autologous PBLs from a patient with MUC1-positive cancer are transduced with a retroviral vector that encodes the CAR gene specific for MUC1. After expansion in culture and reintroduction into the patient, anti-MUC1 CAR-transduced autologous T lymphocytes target and induce selective toxicity in MUC1-expressing tumor cells. MUC-1 is a human, hypoglycosylated tumor-associated antigen (TAA) overexpressed by epithelial cancer cells.

单词	anti-MUC1 CAR-transduced autologous T lymphocytes
释义	anti-MUC1 CAR-transduced autologous T lymphocytes Autologous T lymphocytes transduced with a retroviral vector expressing a chimeric antigen receptor (CAR) consisting of a single chain variable fragment (scFv) against the human tumor-associated epithelial antigen mucin 1 (MUC1), with potential immunomodulating and antineoplastic activities. Autologous PBLs from a patient with MUC1-positive cancer are transduced with a retroviral vector that encodes the CAR gene specific for MUC1. After expansion in culture and reintroduction into the patient, anti-MUC1 CAR-transduced autologous T lymphocytes target and induce selective toxicity in MUC1-expressing tumor cells. MUC-1 is a human, hypoglycosylated tumor-associated antigen (TAA) overexpressed by epithelial cancer cells.
随便看	Arcoxia arctigenin arctiin Aredia areola arginine arginine butyrate arginine/omega-3 fatty acids/nucleotides oral supplement ArginMax argon beam coagulator ablation Aricept Arimidex Aristocort Aristocort A Arixtra ARMD armodafinil ARMS Arnebia Indigo Jade Pearl topical cream Aromasin aromatase inhibitor aromatherapist aromatherapy aromatherapy infusion aromatherapy massage