A major incident that occurred in the UK in 1974. It involved an explosion at the Flixborough Works of Nypro (UK) Limited near Hull, killing 28 people and injuring 36 others, together with extensive damage beyond the factory including 2,000 houses and 200 shops and factories. The incident took place on 1 June 1974 and was the result of a massive leak and subsequent deflagration of cyclohexane gas from a temporary bypass in a chain of six reactors. The reactors were used for the oxidation of cyclohexane to form cyclohexanone and cyclohexanol by the injection of air in the presence of catalyst. The cyclohexane and cyclohexanol were in subsequent stages of the process for conversion to caprolactum, which is a raw material for the production of Nylon 6. At the time, the report from the Court of Enquiry was the most comprehensive inquiry into a disaster in the chemical industry, and was crucial in the development of Loss Prevention in the UK.