Entner-Doudoroff pathway [¦ent·nǝr ¦dō·dǝ´rȯf ´path´wā] BIOCHEMISTRY A sequence of reactions for glucose degradation, with the liberation of energy; the distinguishing feature is the formation of 2-keto-3-deoxy-6-phosphogluconate from 6-phosphogluconate and the cleaving of this compound to yield pyruvate and glyceraldehyde-3- phosphate. |