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选择性IgA缺陷
释义
选择性IgA缺陷
Encyclopedia
医学
原发性B细胞缺陷
释
selective IgA deficiency
选择性IgA缺陷
常染色体显性或隐性遗传的体液免疫缺陷。是最常见的一种原发性免疫缺陷病,任何年龄段人群均可发病,但以儿童多见。患者常伴有自身免疫病和超敏反应性疾病。发病机制可能与B细胞分化缺陷或辅助性T细胞功能缺陷有关,可能是非免疫球蛋白基因区的某个基因异常所致,而并非IgA基因缺陷。
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