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药物生殖毒性试验
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药物生殖毒性试验
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医学
药物生殖毒性试验
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reproductive and developmental toxicity study for drugs
药物生殖毒性试验
用于评价药物对雌、雄生殖系统及功能和发育过程影响的动物试验研究。包括对亲代动物生殖能力的结构和功能性改变(包括对生殖细胞、受孕、分娩和哺乳等毒性影响)和子代(胚胎-胎仔、幼仔)的发育毒性影响(包括死亡、畸形、生长异常和功能性毒性等)的评价。
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