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complement activation lectin pathway
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complement activation lectin pathway
Encyclopedia
医学
补体激活途径
释
complement activation lectin pathway
补体激活凝集素途径
血浆中甘露聚糖结合凝集素(MBL[注])或纤胶凝蛋白(FCN[注])直接识别多种病原微生物表面的N-氨基半乳糖或甘露糖,进而依次活化MBL相关丝氨酸蛋白酶-1(MASP-1[注])、MASP-2、C4、C2、C3,形成与经典途径相同的C3与C5转化酶的级联酶促反应过程。
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