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内源性抗原
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内源性抗原
Encyclopedia
医学
抗原
释
endogenous antigen
内源性抗原
在抗原提呈细胞及宿主细胞内新合成的抗原。如病毒感染细胞合成的病毒蛋白、肿瘤细胞内合成的肿瘤抗原等。内源性抗原多存在于胞质,遵循胞质溶胶途径(MHCⅠ类分子途径),以抗原肽-MHCⅠ类分子复合物形式提呈给CD8+T细胞。
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