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互补决定区植入抗体
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互补决定区植入抗体
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CDR grafting antibody
互补决定区植入抗体
将异源抗体的互补决定区(complementarity determining region,CDR)移植至人源抗体的可变区骨架中,替代人源抗体CDR而形成的人源化抗体(见图)。又称改型抗体。
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