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transcription activator-like effector nuclease,TALEN
释义
transcription activator-like effector nuclease,TALEN
Encyclopedia
理学
基因工程
释
transcription activator-like effector nuclease,TALEN
转录激活因子样效应物核酸酶
人工合成的基因组编辑核酸酶。由转录激活因子样效应物Tale蛋白的DNA结合结构域与FokⅠ内切核酸酶的催化结构融合而成,可切割特定基因组位点,从而实现基因的敲除、敲入及定点突变等基因组靶向修饰。
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