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pharmacokinetic-pharmacodynamic model
释义
pharmacokinetic-pharmacodynamic model
Encyclopedia
医学
药动学-药效学结合模型
释
pharmacokinetic-pharmacodynamic model
药动学-药效学结合模型
通过效应室将经典的药物代谢动力学(pharmacokinetics)和药效动力学(pharmacodynamics)模型有机地结合起来,揭示血药浓度-时间-效应三者之间的内在联系,即血药浓度随时间和浓度的变化规律,并可定量地反映药物暴露量与效应之间关系的模型。有助于更为全面和准确地了解药物的效应随剂量、浓度及时间而变化的规律。简称PK-PD模型。又称效应室模型。
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