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knock-out of metabolic pathway
释义
knock-out of metabolic pathway
Encyclopedia
理学
代谢途径敲除
释
knock-out of metabolic pathway
代谢途径敲除
在了解微生物代谢途径相关基因信息的基础上,以基因敲除技术为依托,通过构建合适的基因敲除工具,对代谢途径中的某些基因进行敲除,以阻断代谢旁路,防止有毒产物或副产物形成,解除反馈抑制,促进目的代谢产物积累,最终达到优化代谢途径,调节代谢流的目的的技术。
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