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first pass effect
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first pass effect
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首过效应
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first pass effect
首过效应
口服药物经胃肠道(壁)和肝脏后进入体循环,药物在到达体循环之前,经肠道、肠壁和肝的代谢分解,使进入体内的相对药量降低的现象。
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