“anti-ErbB3 monoclonal antibody KTN3379”的概念、定义、翻译、参考文献-科学参考

A monoclonal antibody directed against the human epidermal growth factor receptor ErbB3 (Her3) with potential antineoplastic activity. Anti-ErbB3 monoclonal antibody KTN3379 binds to and prevents ligand binding to ErbB3, which may inhibit ErbB3-dependent phosphatidylinositol-3 kinase (PI3K)/Akt signaling and may lead to the inhibition of cellular proliferation and differentiation. ErbB3, a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases, is frequently overexpressed in a variety of solid tumors and its overexpression generally correlates with poor prognosis and tumor resistance.

单词	anti-ErbB3 monoclonal antibody KTN3379
释义	anti-ErbB3 monoclonal antibody KTN3379 A monoclonal antibody directed against the human epidermal growth factor receptor ErbB3 (Her3) with potential antineoplastic activity. Anti-ErbB3 monoclonal antibody KTN3379 binds to and prevents ligand binding to ErbB3, which may inhibit ErbB3-dependent phosphatidylinositol-3 kinase (PI3K)/Akt signaling and may lead to the inhibition of cellular proliferation and differentiation. ErbB3, a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases, is frequently overexpressed in a variety of solid tumors and its overexpression generally correlates with poor prognosis and tumor resistance.
随便看	gonioscopy Gonzalez regimen Goodbelly Probiotic Good Clinical Practice Gorlin syndrome goserelin acetate gossypol gossypol gossypol acetic acid gp100 gp100:154-162 peptide vaccine gp100:209-217(210M) peptide vaccine gp100:209-217(210M) peptide vaccine gp100:280-288(288V) peptide vaccine gp100 antigen gp100-fowlpox vaccine gp209-2M GP2 peptide/GM-CSF vaccine gp96 heat shock protein-peptide complex vaccine gp96 HSP-peptide complex gp96-secreting allogeneic bladder cancer cell vaccine HS-410 GPI-0100 G protein G-protein linked receptor GPX-100