“MVA-EBNA1/LMP2 vaccine”的概念、定义、翻译、参考文献-科学参考

A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the gene for the CD4 epitope-rich C-terminal domain of the Epstein Barr Virus (EBV) antigen EBNA1 and fused to the full-length of the EBV-associated antigen latent membrane protein 2 (LMP2), with potential immunostimulatory and antineoplastic activities. Upon administration, MVA EBNA1/LMP2 vaccine may elicit a cytotoxic T-cell immune response against cancer cells expressing EBNA1 and LMP2. Multi-antigen vaccine therapy may be more efficacious than single-antigen vaccine therapy. EBNA1, a sequence-specific DNA binding protein, plays an important role in EBV episomal genome maintenance and gene transactivation. Check for active clinical trials using this agent.

单词	MVA-EBNA1/LMP2 vaccine
释义	MVA-EBNA1/LMP2 vaccine A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the gene for the CD4 epitope-rich C-terminal domain of the Epstein Barr Virus (EBV) antigen EBNA1 and fused to the full-length of the EBV-associated antigen latent membrane protein 2 (LMP2), with potential immunostimulatory and antineoplastic activities. Upon administration, MVA EBNA1/LMP2 vaccine may elicit a cytotoxic T-cell immune response against cancer cells expressing EBNA1 and LMP2. Multi-antigen vaccine therapy may be more efficacious than single-antigen vaccine therapy. EBNA1, a sequence-specific DNA binding protein, plays an important role in EBV episomal genome maintenance and gene transactivation. Check for active clinical trials using this agent.
随便看	VAS vascular vascular bundle vascular cambium vascular disrupting agent BNC105P vascular endothelial growth factor antisense oligonucleotide vascular endothelial growth factor-antisense oligonucleotide vascular endothelial growth factor receptor tyrosine kinase inhibitor vascular endothelial growth factor trap vascular endothelial growth factor vascularized autologous bone graft vascular plants vascular tissue vascular tissue system vascular tumor vas deferens vas deferens pl. vasa deferentia vasectomy vasoactive vasoactive intestinal peptide Vasomax vasomotor Vasotec Vasovist vatalanib