“MTF-1 inhibitor APTO-253 HCl”的概念、定义、翻译、参考文献-科学参考

The hydrochloride salt of a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF-1 inhibitor APTO-253 inhibits MTF-1 activity and thereby induces the expression of MTF-1 dependent tumor suppressor factor Kruppel like factor 4 (KLF4). This subsequently leads to the downregulation of cyclin D1, blocking cell cycle progression and proliferation. This agent also causes decreased expression of genes involved in tumor hypoxia and angiogenesis.

单词	MTF-1 inhibitor APTO-253 HCl
释义	MTF-1 inhibitor APTO-253 HCl The hydrochloride salt of a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF-1 inhibitor APTO-253 inhibits MTF-1 activity and thereby induces the expression of MTF-1 dependent tumor suppressor factor Kruppel like factor 4 (KLF4). This subsequently leads to the downregulation of cyclin D1, blocking cell cycle progression and proliferation. This agent also causes decreased expression of genes involved in tumor hypoxia and angiogenesis.
随便看	electronic medical record electron microscope electron microscope (EM) Electron pair electron shell electron transport chain Electron volt Electron volt electrophoresis electroporation therapy electroshock therapy electrosurgery Element Element element element Elementary Particle elesclomol elesclomol sodium Elidel Eligard eligibility criteria Eliquis ELISA elisidepsin