An abbreviation for a combination chemotherapy regimen that is used to treat colorectal cancer. It includes the drugs leucovorin calcium (folinic acid), fluorouracil, and oxaliplatin. There are several different FOLFOX regimens that differ in the doses and ways in which the three drugs are given. Also called mFOLFOX-6, mFOLFOX-6 regimen, and modified FOLFOX-6.