“antibody-drug conjugate ABBV-085”的概念、定义、翻译、参考文献-科学参考

An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against a tumor-associated antigen (TAA) linked to an as of yet undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of ABBV-085 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an as of yet unknown mechanism of action. Check foractive clinical trials using this agent.

单词	antibody-drug conjugate ABBV-085
释义	antibody-drug conjugate ABBV-085 An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against a tumor-associated antigen (TAA) linked to an as of yet undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of ABBV-085 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an as of yet unknown mechanism of action. Check foractive clinical trials using this agent.
随便看	hydrolysis hydrolysis hydromorphone hydrochloride hydromorphone hydrochloride hydronephrosis hydrophilic hydrophobic Hydrostat Hydrostatic Equilibrium hydrostatic skeleton Hydrostat IR hydroureter hydroxychloroquine hydroxychloroquine hydroxydaunorubicin hydroxyl group hydroxymethylglutaryl-coenzyme A reductase inhibitor hydroxytyrosol hydroxyurea hydroxyurea hygiene hygiene Hymorphan hyperactivity HyperAcute-Lung Cancer Vaccine