“JAK2 inhibitor XL019”的概念、定义、翻译、参考文献-科学参考

单词	JAK2 inhibitor XL019
释义	JAK2 inhibitor XL019 An orally bioavailable inhibitor of Janus-associated kinase 2 (JAK2) with potential antineoplastic activity. XL019 inhibits the activation of JAK2 as well as the mutated form JAK2V617F, which may result in the inhibition of the JAK-STAT signaling pathway and may induce apoptosis. The JAK2 mutated form JAK2V617F has a valine-to-phenylalanine modification at position 617 and plays a key role in tumor cell proliferation and survival.
随便看	double balloon endoscopy double-blinded double circulation double-contrast barium enema double fertilization double helix double heterozygosity double-hit lymphoma doubling time douche dovitinib lactate Dovonex Down syndrome Down syndrome doxazosin doxazosin mesylate doxepin hydrochloride doxercalciferol doxifluridine DOXIL Doxil doxorubicin doxorubicin-eluting beads doxorubicin-HPMA conjugate doxorubicin hydrochloride

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