An I 131 radioiodinated synthetic analogue of the neurotransmitter norepinephrine. Iobenguane localizes to adrenergic tissue and, in radioiodinated forms, may be used to image or eradicate tumor cells that take up and metabolize norepinephrine. Check foractive clinical trials using this agent. or A drug containing a form of radioactive iodine called I 131 that is used to find or treat certain types of tumors, including pheochromocytomas and neuroblastomas. It is also used to relieve pain caused by cancer that has spread to the bones. Radiation from the I 131 may help kill cancer cells or show where they are in the body. Iobenguane I 131 is a type of radioimaging agent and a type of radioconjugate. Also called 131I-MIBG and iodine I 131 metaiodobenzylguanidine.