“androgen receptor antisense oligonucleotide AZD5312”的概念、定义、翻译、参考文献-科学参考

单词	androgen receptor antisense oligonucleotide AZD5312
释义	androgen receptor antisense oligonucleotide AZD5312 An antisense oligonucleotide targeting the androgen receptor (AR) mRNA, with potential antineoplastic activity. Upon intravenous administration, AZD5312 hybridizes with AR mRNA, which blocks translation of the AR protein. This both inhibits AR-induced tumor cell growth and promotes apoptosis in AR-overexpressing tumor cells. AR is overexpressed in certain breast and prostate cancers and is involved in tumor cell proliferation and survival.
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