“HSP90 inhibitor PU-H71”的概念、定义、翻译、参考文献-科学参考

A purine-based heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor PU-H71 specifically inhibits active Hsp90, thereby inhibiting its chaperone function and promoting the proteasomal degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. This may result in the inhibition of cellular proliferation in susceptible tumor cell populations. Hsp90, a molecular chaperone protein, is upregulated in a variety of tumor cell types.

单词	HSP90 inhibitor PU-H71
释义	HSP90 inhibitor PU-H71 A purine-based heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor PU-H71 specifically inhibits active Hsp90, thereby inhibiting its chaperone function and promoting the proteasomal degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. This may result in the inhibition of cellular proliferation in susceptible tumor cell populations. Hsp90, a molecular chaperone protein, is upregulated in a variety of tumor cell types.
随便看	dose-rate dosimetrist dosimetry Dostinex DOT1L inhibitor EPZ-5676 DOTAREM double balloon endoscopy double-blinded double circulation double-contrast barium enema double fertilization double helix double heterozygosity double-hit lymphoma doubling time douche dovitinib lactate Dovonex Down syndrome Down syndrome doxazosin doxazosin mesylate doxepin hydrochloride doxercalciferol doxifluridine