“Hsp90 inhibitor CNF2024”的概念、定义、翻译、参考文献-科学参考

An orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90 inhibitor CNF2024 specifically blocks active HSP90, inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival; this may result in the inhibition of cellular proliferation in susceptible tumor cell populations. HSP90, a chaperone protein upregulated in a variety of tumor cell types, regulates the folding and degradation of many oncogenic signaling proteins.

单词	Hsp90 inhibitor CNF2024
释义	Hsp90 inhibitor CNF2024 An orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90 inhibitor CNF2024 specifically blocks active HSP90, inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival; this may result in the inhibition of cellular proliferation in susceptible tumor cell populations. HSP90, a chaperone protein upregulated in a variety of tumor cell types, regulates the folding and degradation of many oncogenic signaling proteins.
随便看	Celsius scale of temperature CEM CEM regimen cenersen cenisertib Cenolate Centers for Disease Control and Prevention Centigrade centimeter central nervous system central nervous system (CNS) central nervous system depressant central nervous system metastasis central nervous system primitive neuroectodermal tumor central nervous system prophylaxis central nervous system sanctuary therapy central nervous system stimulant central nervous system tumor central venous access catheter Centrifugal force Centrifugal force centriole Centripetal force Centripetal force centromere