A regimen consisting of fluorouracil and leucovorin, used in both the adjuvant and metastatic disease setting, for the treatment of colorectal cancer. This regimen is also combined with radiation for the treatment of gastric and esophageal cancer. Or An abbreviation for a chemotherapy combination used to treat colorectal cancer. It is also used with radiation therapy to treat esophageal cancer and stomach cancer. It includes the drugs fluorouracil and leucovorin calcium. Also called 5-FU/LV and FU-LV.