“entolimod”的概念、定义、翻译、参考文献-科学参考

A polypeptide derived from the Salmonella filament protein flagellin with potential radioprotective and anticancer activities. As a toll-like receptor 5 (TLR5) agonist, entolimod binds to and activates TLR5 thereby stimulating tumor necrosis factor production and activating nuclear factor kappa B (NF-kB). This induces NF-kB-mediated signaling pathways and inhibits the induction of apoptosis. This may prevent apoptosis in normal, healthy cells during radiotherapy of cancerous cells and may allow for increased doses of ionizing radiation. In addition, entolimod may inhibit radiation-independent proliferation in TLR5-expressing tumor cells.

单词	entolimod
释义	entolimod A polypeptide derived from the Salmonella filament protein flagellin with potential radioprotective and anticancer activities. As a toll-like receptor 5 (TLR5) agonist, entolimod binds to and activates TLR5 thereby stimulating tumor necrosis factor production and activating nuclear factor kappa B (NF-kB). This induces NF-kB-mediated signaling pathways and inhibits the induction of apoptosis. This may prevent apoptosis in normal, healthy cells during radiotherapy of cancerous cells and may allow for increased doses of ionizing radiation. In addition, entolimod may inhibit radiation-independent proliferation in TLR5-expressing tumor cells.
随便看	fluorine F 18 4-L-fluoroglutamine (2S,4R) fluorine F 18 5-fluoro-2-deoxycytidine fluorine F 18 6-fluorodopamine fluorine F 18 alfatide II fluorine F 18 ara-G fluorine F 18-AV-133 fluorine F 18 choline fluorine F 18 CP18 peptide fluorine F 18 dabrafenib fluorine F 18 DCFBC fluorine F 18 DCFPyL fluorine F 18 d-FMAU fluorine F 18 EF5 fluorine F 18 FDHT fluorine F 18 FEQA fluorine F 18 fluciclovine fluorine F 18 fluorobenzyl triphenyl phosphonium fluorine F 18 fluorodopa fluorine F 18 fluoroethylcholine fluorine F 18 fluoro furanyl norprogesterone fluorine F 18 fluoropaclitaxel fluorine F 18 fluoro-PEG6-IPQA fluorine F 18 fluorothymidine fluorine F 18 fluorthanatrace fluorine F 18 FMDHT