“complement C5 inhibitor ALXN1210”的概念、定义、翻译、参考文献-科学参考

A longer-acting antibody directed against terminal complement protein C5, with potential anti-inflammatory activity. Upon administration, complement C5 inhibitor ALXN1210 binds to terminal complement protein C5, thereby blocking C5 cleavage into pro-inflammatory components and preventing the complement-mediated destruction of red blood cells (RBCs) as seen in paroxysmal nocturnal hemoglobinuria (PNH). Compared to other anti-C5 antibodies, ALXN1210 is longer-acting and allows for monthly dosing. C5, a complement pathway protein, is expressed at high levels by the liver.

单词	complement C5 inhibitor ALXN1210
释义	complement C5 inhibitor ALXN1210 A longer-acting antibody directed against terminal complement protein C5, with potential anti-inflammatory activity. Upon administration, complement C5 inhibitor ALXN1210 binds to terminal complement protein C5, thereby blocking C5 cleavage into pro-inflammatory components and preventing the complement-mediated destruction of red blood cells (RBCs) as seen in paroxysmal nocturnal hemoglobinuria (PNH). Compared to other anti-C5 antibodies, ALXN1210 is longer-acting and allows for monthly dosing. C5, a complement pathway protein, is expressed at high levels by the liver.
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