“adenovirus-mediated human interleukin-12”的概念、定义、翻译、参考文献-科学参考

A replication-incompetent adenovirus encoding human pro-inflammatory cytokine interleukin-12 (IL-12) (Ad.hIL-12), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration, the adenovirus selectively infects and replicates in tumor cells, which may result in tumor cell lysis. Synergistically, IL-12 expressed by the adenovirus may activate the immune system by promoting the activation of natural killer cells (NKs), inducing secretion of interferon-gamma and inducing cytotoxic T cell responses against tumor cells, which may result in immune-mediated tumor cell death and inhibition of tumor cell proliferation.

单词	adenovirus-mediated human interleukin-12
释义	adenovirus-mediated human interleukin-12 A replication-incompetent adenovirus encoding human pro-inflammatory cytokine interleukin-12 (IL-12) (Ad.hIL-12), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration, the adenovirus selectively infects and replicates in tumor cells, which may result in tumor cell lysis. Synergistically, IL-12 expressed by the adenovirus may activate the immune system by promoting the activation of natural killer cells (NKs), inducing secretion of interferon-gamma and inducing cytotoxic T cell responses against tumor cells, which may result in immune-mediated tumor cell death and inhibition of tumor cell proliferation.
随便看	Stromagen stromal cell stromal tumor stromatolite Strong Nuclear Force strontium strontium-89 strontium chloride Sr 89 strontium ranelate structural formula structural gene study agent Sturge-Weber syndrome style SU006668 SU011248 SU014813 SU101 SU11248 SU5416 SU6668 subarachnoid block subcutaneous subcutaneous port subependymal