“bimagrumab”的概念、定义、翻译、参考文献-科学参考

A human monoclonal antibody directed against type II activin receptors (ActRII; ActR2), with potential muscle-sparing and anti-cachectic activities. Upon administration, bimagrumab binds to ActRII, which prevents the binding of the natural ligands, myostatin and activin, to activin receptors and blocks ActRII-mediated signaling. This increases protein synthesis, decreases protein degradation, stimulates skeletal muscle cell growth, and increases muscle function and strength. Overstimulation of the ActRII-mediated signaling pathway is associated with muscle loss and weakness.

单词	bimagrumab
释义	bimagrumab A human monoclonal antibody directed against type II activin receptors (ActRII; ActR2), with potential muscle-sparing and anti-cachectic activities. Upon administration, bimagrumab binds to ActRII, which prevents the binding of the natural ligands, myostatin and activin, to activin receptors and blocks ActRII-mediated signaling. This increases protein synthesis, decreases protein degradation, stimulates skeletal muscle cell growth, and increases muscle function and strength. Overstimulation of the ActRII-mediated signaling pathway is associated with muscle loss and weakness.
随便看	reconstructive surgery Recormon recover recreational therapy rectal rectal cancer rectal reconstruction Rectilinear Motion Rectilinear Motion rectitis Rectoid rectum recur recurrence recurrence risk recurrent cancer red blood cell red cedar red clover red date red elm redox redox reaction Redshift red tomato juice