An orally bioavailable tyrosine kinase inhibitor. Axitinib inhibits the proangiogenic cytokines vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor (PDGF), thereby exerting an anti-angiogenic effect. Check for active clinical trialsusing this agent. or A lymph node in the armpit region that drains lymph from the breast and nearby areas.