“TORC1/2 kinase inhibitor DS-3078a”的概念、定义、翻译、参考文献-科学参考

单词	TORC1/2 kinase inhibitor DS-3078a
释义	TORC1/2 kinase inhibitor DS-3078a An orally bioavailable inhibitor of raptor-mTOR protein complex (TORC1) and rictor-mTOR protein complex (TORC2) with potential antineoplastic activity. TORC1/2 inhibitor DS-3078a binds to and inhibits both TORC1 and TORC2 , which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some tumors and play an important role in the PI3K/Akt/mTOR signaling pathway, which is frequently dysregulated in human cancers.
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