单词 | topoisomerase I inhibitor Genz-644282 |
释义 | topoisomerase I inhibitor Genz-644282 A non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations. Check for active clinical trialsusing this agent. |
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