释义 |
SarCNU An alkylating chloroethylnitrosourea with antineoplastic activity. Selectively accumulating in some tumor cells, SarCNU forms covalent linkages with nucleophilic centers in DNA, causing depurination, base pair miscoding, strand scission, and DNA-DNA cross-linking, which may result in cytotoxicity. or A substance being studied in the treatment of cancer. It is a type of alkylating agent. Also called sarcosinamide nitrosourea. |