请输入您要查询的字词:

 

单词 sagopilone
释义
sagopilone
A fully synthetic low-molecular-weight epothilone with potential antineoplastic activity. Sagopilone binds to tubulin and induces microtubule polymerization while stabilizing microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. The agent is not a substrate for the P-glycoprotein (P-gp) efflux pump and so may exhibit activity in multidrug-resistant (MDR) tumors. The epothilone class of metabolites was originally isolated from the myxobacterium Solangium cellulosum. 
随便看

 

科学参考收录了15208条科技类词条,基本涵盖了常见科技类参考文献及英语词汇的翻译,是科学学习和研究的有利工具。

 

Copyright © 2000-2023 Sciref.net All Rights Reserved
京ICP备2021023879号 更新时间:2024/6/30 19:01:14