“Raf kinase inhibitor XL281”的概念、定义、翻译、参考文献-科学参考

单词	Raf kinase inhibitor XL281
释义	Raf kinase inhibitor XL281 An orally active, small molecule with potential antineoplastic activity. XL281 specifically inhibits RAF kinases, located downstream from RAS in the RAS/RAF/MEK/ERK kinase signaling pathway, which may result in reduced proliferation of tumor cells. RAS mutations may result in constitutive activation of the RAS/RAF/MEK/ERK kinase signaling pathway, and have been found to occur frequently in human tumors. Check for active clinical trialsusing this agent.
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