“anti-prolactin receptor antibody LFA102”的概念、定义、翻译、参考文献-科学参考

A neutralizing antibody against the prolactin receptor (PRLR) with potential antineoplastic activity. Upon administration, anti-prolactin receptor antibody LFA102 binds to PRLR and prevents the binding of the peptide hormone prolactin (PRL) to its receptor. This binding induces an antibody-dependent cellular cytotoxicity (ADCC) and may eventually prevent tumor cell proliferation in PRLR-positive cancer cells. PRLR/PRL signaling pathway is frequently overexpressed in breast and prostate cancer. Check for active clinical trialsusing this agent.

单词	anti-prolactin receptor antibody LFA102
释义	anti-prolactin receptor antibody LFA102 A neutralizing antibody against the prolactin receptor (PRLR) with potential antineoplastic activity. Upon administration, anti-prolactin receptor antibody LFA102 binds to PRLR and prevents the binding of the peptide hormone prolactin (PRL) to its receptor. This binding induces an antibody-dependent cellular cytotoxicity (ADCC) and may eventually prevent tumor cell proliferation in PRLR-positive cancer cells. PRLR/PRL signaling pathway is frequently overexpressed in breast and prostate cancer. Check for active clinical trialsusing this agent.
随便看	Carnitor carnivore Carnot's theorem carotenoid carotenoids carotid artery carpel carrageenan-containing gel carrier carrier frequency carrier oil carrier rate carrot/Ji-Lin ginseng/licorice root/tangerine peel soy beverage carrying capacity cART CAR T-cell therapy cartilage cartilage carubicin carvedilol carvedilol phosphate carvedilol phosphate extended-release capsule carzelesin case-control study caseinate protein isolate