“primary prostate cancer tissue/hTERT/survivin mRNA-loaded autologous dendritic cell vaccine”的概念、定义、翻译、参考文献-科学参考

单词	primary prostate cancer tissue/hTERT/survivin mRNA-loaded autologous dendritic cell vaccine
释义	primary prostate cancer tissue/hTERT/survivin mRNA-loaded autologous dendritic cell vaccine An autologous dendritic cell (DCs) vaccine targeting prostate cancer with immunostimulating activity. The autologous DC vaccine is prepared via transfecting DCs with mRNAs extracted from primary prostate cancer tissue, and mRNAs of human telomerase reverse transcriptase (hTERT) and survivin. Upon administration, this DC vaccine may elicit a potent cytotoxic T-cell (CTL) response against prostate cancer cells, resulting in tumor cell death. Both hTERT and survivin are essential in neoplastic growth, and are considered to be universal tumor antigens.
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