“PI3K inhibitor PX-866”的概念、定义、翻译、参考文献-科学参考

A small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity. PI3K inhibitor PX-866 inhibits the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.

单词	PI3K inhibitor PX-866
释义	PI3K inhibitor PX-866 A small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity. PI3K inhibitor PX-866 inhibits the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.
随便看	well-differentiated lymphocytic lymphoma Wermer syndrome Western medicine wheatgrass juice whey protein isolate whey protein powder Whipple procedure white blood cell white button mushroom extract white carrot White Hole white wine Whitmore-Jewett staging system WHO whole-brain radiation therapy whole-brain radiotherapy whole cell vaccine whole-exome sequencing whole-genome sequencing whooping cough wide local excision Wien's displacement law wild clover wild type wild-type reovirus