“pan-RAF kinase inhibitor TAK-580”的概念、定义、翻译、参考文献-科学参考

单词	pan-RAF kinase inhibitor TAK-580
释义	pan-RAF kinase inhibitor TAK-580 An orally available inhibitor of A-Raf, B-Raf and C-Raf protein kinases, with potential antineoplastic activity. Upon administration, pan-RAF kinase inhibitor TAK-580 inhibits Raf-mediated signal transduction pathways, which may inhibit tumor cell growth. Raf protein kinases play a key role in the RAF/MEK/ERK signaling pathway, which is often deregulated in human cancers and plays a key role in tumor cell proliferation and survival. Check foractive clinical trials using this agent.
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